Tier B · Substantial human research
Thymosin Beta-4
One of the better human-researched tissue-repair peptides—especially in ophthalmology.
Why researchers care
Potential human relevance
- Phase 2 human studies reported improvement in signs and symptoms of dry eye
- Human phase 1 systemic studies evaluated safety and pharmacokinetics
- Broad wound-healing and cell-migration biology has been studied extensively
What the human evidence says
Evidence, not extrapolation
Native thymosin beta-4 has real human trial data. “TB-500,” however, is a research-market term that should not automatically be treated as identical to every clinical thymosin beta-4 formulation.
How to think about it
The Yooper Peptides take
This distinction matters: clinical evidence belongs to the exact molecule, formulation and route that was studied.
Primary / authoritative reading